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A 10 Day Sicily Road Trip: The Best Things to Do, See, and Eat

Plan a 10 day Sicily road trip with this helpful guide. Explore Sicily from Siracusa to Palermo. Discover things to do in Sicily on a road trip.
We enjoy European road trips and a Sicily road trip has been on our bucket list for some time now; ever since Ryanair introduced direct flights to Sicily from Dublin.

Sicily embodies thousands of years of history spanning the height of the Greek and Roman empires. The Baroque churches of the Middles Ages in Sicily can't be beat.

As in other parts of Italy, Sicily's food and wine culture is particularly strong, not to mention excellent value for money.

We finally found time for a 10 day Sicilian road trip in May. Here is my advice on making the most of a Sicily road trip itinerary.

Road trip in Sicily - Angel Statues in Modica

Our 10 Day Sicily Road Trip Itinerary at a Glance

Let's start with a quick sketch of our Sicily road trip itinerary to inspire ideas of where to go and what to do if you have 10 days for your trip. 
  • Day 1: Arrive in Sicily (Siracusa) - check into La Via della Guidecca
  • Day 2: Explore Siracusa
  • Day 3: Siracusa to Modica via Riserva Naturale Orientata Oasi Faunistica di Vendicari and Noto - check into FerroHotel
  • Day 4: Modica
  • Day 5: Modica to Ragusa and onward to Piazza Armerina - check into Villa Clementine
  • Day 6: Piazza Armerina to Palermo via Enna
  • Day 7-9: Palermo - check into C'era Una Volta
  • Day 10: Depart Sicily (Palermo)
Now join me as we dive into this Sicily road trip itinerary in more detail.


We flew from Dublin to Catania on the east coast of Sicily and drove to Siracusa (aka Syracuse). The town is known for its Greek history and culture and is the birthplace of Archimedes, the ancient mathematician.

We parked our car in a lot on the outskirts of town and spent two lovely days exploring the atmospheric old town of Siracusa on the Island of Ortigia on foot.

Sicilian Fountains

Road trip in Sicily - Fonte de Artemis in Siracusa

The fountains in Ortigia were particularly impressive. All roads seemed to lead to the Baroque Fonte de Artemis which recounts a key story of Greek mythology where Artemis (Diana in Roman mythology) changed Arethusa into a spring of water to escape the river god Alpheus.

In modern day Siracusa, the fountain served as a convenient anchor point for our exploration.

Seaside Walks on Ortigia Island

Road trip in Sicily - Siracusa seaside

Ortigia Island featured plenty of coastline. We spent a good few hours soaking in the sun and staring out at the crystal clear blue waters of the Mediterranean.

Sicilian Baroque Churches

Road trip in Sicily - Baroque church in Siracusa

Piazza Duomo, a large Baroque square featuring the catedral and other Baroque buildings added great atmosphere to our visit to Siracusa.

We enjoyed exploring and photographing the various Baroque churches of Ortigia both inside and out. Piazza Duomo was a great place to concentrate our exploration.

Aresthusa Fountain and the Papyrus Grotto of Siracusa

Road trip in Sicily - Arethusa Fountain and papyrus in Siracusa

Continuing the story of Arethusa, once Artemis turned Arethusa into a spring to escape Alpheus, her water flowed into the sea at this very spot. Alpheus continued his pursuit and came gushing out in this same spot mixing their waters for all eternity.

Coming back to the real world for a moment, this grotto on the Island of Ortigia in Sicily is the only spot outside of Greece where papyrus (crucial for ancient paper-making) grows.

Greek Ruins near Siracusa

Road trip in Sicily - Greek Theatre in Siracusa

Venturing out from Ortigia back into Siracusa, we visited the Greek Theatre of Syracuse. We liked to imagine ourselves as ancient theatre-goers checking out a performance.

In fact, the venue is still used for live performances today. When we visited, Siracusa was gearing up for the annual Greek Theatre Festival.

In addition to the Greek ruins, the site also features some short hiking trails and the Ear of Dionysus, a cave rumored to have been used by Dionysius I to imprison dissidents and eavesdrop on their plans thanks to the outstanding acoustics in the cave.

Boats in the Harbor

Road trip in Sicily - Boats in the Harbor at Ortigia Island

Walking back toward Ortigia island, we stopped to admire the colorful boats moored in the harbour.

Stunning Sicilian Sunsets

Road trip in Sicily - Sunset in Siracusa

The waterfront near westward facing Fonte de Arethusa is an ideal spot to watch the sunset over Sicily. The colors and light dappled on the water was amazing to see.

Finding Dire Straits in Siracusa

Thumbnail linking to a video. Band playing Dire Straits in Siracusa SicilyClick on the image of the band to watch the video on YouTube

On our final night in Siracusa, we discovered that Sicily has a fun and quirky side. At dusk, a number of cafes feature musicians playing on the streets.

We stumbled upon a band getting their Dire Straits on. I want my, I want my, I want my MTV... It was just so unexpected to hear a 1980s cover band rocking out in a tucked away corner of Sicily; we couldn't help but smile.


After a lovely couple of days in Siracusa, it was time to retrieve the car and continue our Sicilian road trip. We were headed for Modica and the other Baroque hill towns of Sicily but we decided to stop at the Riserva Naturale Orientata Oasi Faunistica di Vendicari to stretch our legs first.

The Abandoned Tuna Plant

Road trip in Sicily - Abandoned tuna plant

Getting to the reserve requires a leap of faith to turn off the highway onto a super narrow dirt road. We drove to a small parking lot at the very end of the road and then continued on foot toward the sea.

Our jaws dropped in awe when we spotted the brilliant blue water against a backdrop of an abandoned tuna plant.

Scurrying Sicilian Lizards

Road trip in Sicily - Lizard on the boardwalk

To get to the beach, we traipsed across a creaky boardwalk. Small lizards scurried to and fro when they felt the vibrations of our steps.

The Flamingos of Sicily

Road trip in Sicily - Flamingoes

The reserve is also home seasonally to a flock of flamingoes. We visited at the tail end of the season but were fortunate to spot a few flamingoes dozing in the distance. Such majestic creatures!

🔎 Love flamingos? Then don't miss a trip to the Camargue near Montpellier, a great spot to see and photograph flamingos.

Sicilian Swifts

Road trip in Sicily - Swift (bird)
We also found that the reserve (and Sicily in general) was full of swifts darting to and fro. A good number seemed to live in the eaves of the Baroque buildings. We had a fantastic time watching them buzz here and there.


A great earthquake destroyed much of Sicily in 1693. From the rubble emerged the Baroque-style architecture that Sicily is most famous for. The Baroque hill towns of Noto, Modica, and Ragusa were definitely highlights of our 10 day road trip in Sicily.

The Baroque towns are also quite difficult to visit without the freedom that comes with renting a car.


Road trip in Sicily - Church in Noto

Our first stop on our road trip in Sicily was Noto. Known equally for its architecture and for having the best gelato in the world, we spent a sunny afternoon exploring church after church inside and out.

There are a number of outdoor cafes and gelato shops to steep in the atmosphere. Note: many cafes are closed on Monday (when we visited) which meant we had to try a bit harder to find a place for lunch.
Road trip in Sicily - Baroque church in Noto


Road trip in Sicily - angel statues in Modica

We drove into Modica just before dusk, dropped off the car, and set off to explore the town on foot. Modica not only features amazing Baroque architecture but also its very own kind of chocolate.

Practically every other shop is a Modica chocolatier offering generous samples. I could get used to this! To learn more about the fabulous foods of Sicily, check out this post.
Road trip in Sicily - Modica

The next day, we set off on a walk across town. Modica is situated on two distinct hillsides.

Definitely take the time to get lost while climbing further and further upwards. We admired the sooty stone buildings from above.

I loved how the town seemed to just spill over the hillside. Modica offers some amazing opportunities for a photo walk.
Road trip in Sicily - Modica


Road trip in Sicily - Ragusa

After two nights in Modica, we were ready to continue our Sicily road trip by setting a course for Ragusa, the third in the trio of famous Baroque hill towns.
Road trip in Sicily - Baroque Church in Ragusa

We spent a couple hours exploring the town on foot. Ragusa sits across two separate hills and we ended up climbing them both.

We definitely worked for it and were huffing and puffing by the time we were done, but it was totally worth it for the brilliant photo opportunities at the top.
Road trip in Sicily - Looking up in Ragusa


Continuing our travels by car, we spent about half a day and a single night in the town of Piazza Armerina. The town is famous for the nearby Villa Romana del Casale, a well-preserved Roman townhouse with stunning mosaics.

🔎 You can also find some amazingly well-preserved Roman mosaics on a road trip in Cyprus and at the main train station on a weekend in Sofia Bulgaria.

The Bikini Girls of Piazza Armerina

Road trip in Sicily - Bikini girls mosaic at Villa Romana del Casale

What was our favorite part about visiting Villa Romana del Casale? The depictions of everyday life in the Roman Empire.

We studied the bikini girls mosaic. Apparently, female athletes would work out in the equivalent of string bikinis. I'm not sure I could have pulled that off back in the day!


We paused our road trip briefly to stretch our legs in Enna before making the final push to Palermo. Enna sits at the top of a hill and we drove our way up a very steep, winding, and narrow backroad to get there.

It was worth it in the end when we parked the car and looked out across the valley and saw Mount Etna hovering like a ghost in the distance.
Road trip in Sicily - Mount Etna viewed from Enna

Enna is incredibly picturesque and features the ruins of Castello di Lombardia which are worth a quick tour. The town lies generally along a single main street and features cafes and coffee shops flanking either side.

Enna is definitely a good spot for a road trip detour while en route by automobile from the Baroque hill towns to Palermo.
Road trip in Sicily - Enna


We were advised not to drive in Palermo because of the narrow streets, chaotic traffic, and crazy drivers. We opted to return the rental car at the airport and take the airport bus into town for a stress free arrival.

We spent the final three nights of our visit to Sicily exploring all that the bustling capital city has to offer.

Palermo's Teatro Politeama Garibaldi

Road trip in Sicily - Teatro Politeama Garibaldi in Palermo

We stayed close to Teatro Politeama Garibaldi which cut a stunning presence on Piazza Ruggero Settimo. I loved how the stain-glassed windows reflected the deep blue of the sky.

Palermo's Crazy Traffic

Road trip in Sicily - Horse and scooter in Palermo

The traffic in Palermo was a bit crazy and we were happy that we'd jettisoned our rental car. Cars weren't the only means of transportation though.

We saw plenty of scooters and horse draw carriages. Make sure to look both ways when crossing the street and keep an eye out for speeding vehicles of all types.


Looking for some other amazing destination ideas in Italy? Why not:
  1. Spend 2 days in Milan on a weekend city break in Italy's fashion capital?
  2. Plan a winter weekend in Venice or Rome?
  3. Find out why Trieste is worth visiting?
  4. Spend the weekend in Bergamo (a top Ryanair destination!) and take a day trip from Bergamo to Lake Iseo?
  5. Plan a weekend in Bologna and then travel from Bologna to Modena to Parma on an Emilia-Romagna food holiday?
  6. Spent a day discovering things to do in Ferrara?
  7. Enjoy the Dolomites by spending a day in Bressanone if you find yourself in Innsbruck, Austria?

Palermo's Cathedral

Road trip in Sicily - Duomo in Palermo

Palermo Cathedral is absolutely huge and takes up an entire city block. In addition to the beautiful facade and gardens, there is a memorial inside to Father Pino Puglisi.

Father Puglisi was known as the anti-mafia priest and paid the ultimate price with his life when a hit was put out on him due to his work to turn around a rough mafia-controlled neighborhood in Palermo. The locals that we talked to looked at Father Puglisi as a local hero.

Ferraris on the Streets of Palermo

There is nothing more stereotypically Italian than fast cars. Imagine our surprise though when we were strolling through Piazza Guiseppe Verdi in front of the Opera House when we found all sorts of people milling about.

Road trip in Sicily - Ferraris at Targa Florio in Palermo

There seemed to be a festival on. We soon heard revving of engines and went in to take a closer look.

Serendipitiously, we had arrived in Palermo on the eve of the annual Targa Florio, a road race through the mountains. Ferrari owners from all over the world had come to Palermo to participate and show off their machismo. Click on the image below to open the video in YouTube.

Video thumbnail showing 2 red Ferraris in Palermo Sicily

A Sicilian Food Tour through Palermo

Road trip in Sicily - Mercato di Capo

One of the major highlights of our visit to Palermo was the Streaty Palermo food tour. Owner and guide, Marco, led us through Mercato di Capo and the surrounding winding pedestrianized streets between Piazza Guiseppe Verdi and the Cathedral.

Along the way, we filled our bellies with authentic Sicilian street food while Marco regaled us with stories of Sicilian food and culture. I even ate a spleen sandwich \o/.
Road trip in Sicily - Taverna in Palermo

Palermo's Opera House

Road trip in Sicily - Teatro Massimo (Opera House)
The Opera house is probably the most famous building in Palermo. It's famous not only for being the third largest opera house in Europe but also for playing a pivotal role in the movie The Godfather III.

Apparently, visiting Americans try to re-enact the final shoot-out on the steps of the Teatro Massimo on a nearly daily basis. We kept our composure and opted to take a brief tour inside instead.

🔎 Looking for other iconic European road trip ideas? Why not drive the Loire Valley in France? You'll find great wine and some of the best castles in the world.

A Day Trip from Palermo to Monreale

Sicily Road Trip - Golden Mosaics in Monreale
We concluded our time in Palermo and our road trip through Sicily with a day trip to Monreale, It's possible to get to Monreale by taking a frequent (but crowded!) public bus service.

It took about 45 minutes to get there overall. The centerpiece of Monreale is the cathedral and associated cloister which are done in Norman style.

The Duomo of Monreale was recently listed as a UNESCO World Heritage Site and features a stunning interior of golden mosaics. I particularly liked the Benedictine Cloister featuring a courtyard lined with decorated pillars. The capitals are each different and feature scenes of life in Sicily at the time.
Road trip in Sicily - Columns at the Benedictine Cloister in Monreale

Our 10 Day Sicily Road Trip Map

Click on the image of the Sicily road trip map below to open up an interactive version in Google Maps to help you plan your 7 day Sicily itinerary.
Road Trip Sicily Map

Summing Up Our 10 Day Sicily Road Trip Itinerary

Overall, we drove a lot of miles on our Sicily road trip. We had a great time driving around Sicily as we steeped in history and architecture.
We ate some of the best food and wine in the world all while having the opportunity to soak in the sun and even take a siesta every afternoon for a bit of socially acceptable relaxation.

If you are looking for a combination of plenty to do while not feeling rushed, a 10 day Sicilian road trip should definitely be on your bucket list.

If you have more than 10 days to spend in Sicily, why not consider adding a stop on the Aeolian Islands for a more off-the-beaten-track adventure.

Looking for other ideas for places to explore in Southern Italy? Hop on over to Next Stop TBC for Top Places to Visit in Naples and the Salento Region.

Read More About Our Road Trip to Sicily

Helpful Links About Visiting Sicily

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10 Day Sicily Road Trip Itinerary

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Sidewalk Safari | Part-time Travel Blog: A 10 Day Sicily Road Trip: The Best Things to Do, See, and Eat
A 10 Day Sicily Road Trip: The Best Things to Do, See, and Eat
Plan a 10 day Sicily road trip with this helpful guide. Explore Sicily from Siracusa to Palermo. Discover things to do in Sicily on a road trip.
Sidewalk Safari | Part-time Travel Blog